New Milestone Trial rau Cov Neeg Mob nrog COPD

dNerva® TLD yog cov txheej txheem bronchoscopic uas cuam tshuam cov hlab ntsha hauv lub ntsws rau hauv lub ntsws kom txo tau qhov tshwm sim ntawm qhov tshwm sim ntawm neural hyperactivity. Mechanistically zoo ib yam li anticholinergics (cov chav kawm tseem ceeb ntawm COPD cov tshuaj) noj txhua hnub los tswj cov tsos mob, tus txheej txheem dNerva ib zaug muaj peev xwm txo qis kev pheej hmoo ntawm exacerbation, txhim kho cov tsos mob, thiab ua kom lub ntsws ua haujlwm.

Kev kho 300th dNerva TLD tshwm sim lub hli no. Dr. Gerard Criner, Tus Thawj Coj thiab Xib Fwb, Thoracic Tshuaj thiab Kev Kho Mob ntawm Lewis Katz Tsev Kawm Ntawv Tshuaj ntawm Tuam Tsev University tau kho 20 tus neeg mob hauv AIRFLOW-3 mus sib hais. "Yog tias peb tuaj yeem pab cov neeg mob kom ruaj khov lawv cov tsos mob COPD thiab ua kom lawv tawm hauv tsev kho mob, qhov ntawd yuav muaj txiaj ntsig zoo rau cov neeg mob, lawv cov neeg saib xyuas, thiab txo lub nra ntawm kev noj qab haus huv ib yam," nws hais. COPD exacerbations sawv cev kwv yees li ob feem peb ntawm tag nrho cov nqi kho mob COPD, kwv yees li ntawm $49B ib xyoos ib zaug hauv Asmeskas

Lub hlis no kuj tseem yog qhov tseem ceeb ntawm kev kho mob tseem ceeb hauv kev sim AIRFLOW-3. Prof. Pallav Shah, Tus Kws Pab Tswv Yim Kho Mob ntawm Chelsea & Westminster thiab Royal Brompton Tsev Kho Mob hauv London thiab tus kws tshaj lij ntawm Cov Tshuaj Kho Mob ntawm Imperial College yog tus thawj coj hauv kev sim. Nws tau ua tus txheej txheem 200th AIRFLOW-3 nyob rau hauv tus neeg mob uas muaj mob nruab nrab-rau-mob COPD, lub nra hnyav, thiab keeb kwm ntawm COPD exacerbations txawm tias kev tswj xyuas kev kho mob zoo. Nws tau hais tias "Ntau tus neeg mob COPD raug kev txom nyem los ntawm kev ua neej tsis zoo vim qhov rov ua rau COPD ntau dua," nws hais. "Qhov kev sim AIRFLOW-3 yog lub sijhawm zoo siab los tshuaj xyuas cov txheej txheem kho mob ib zaug uas tuaj yeem txo qis COPD exacerbations thiab txhim kho kev kho mob kom ruaj ntseg."

Lub Tuam Txhab tsis ntev los no tau txais txiaj ntsig ntxiv $ 50 lab kev cog lus ntawm cov nuj nqis thiab kev ncaj ncees nyiaj txiag nrog Innovatus Capital Partners, LLC, uas yuav siv los ua kom tiav AIRFLOW-3 mus sib hais thiab ua tiav US FDA pom zoo.