Txoj Kev Kawm Tshiab: Ib feem peb ntawm cov poj niam tau txais kev kho mob tsis zoo ntawm Vaginitis

Nyob rau hauv daim ntawv, Performance of a Vaginal Panel Assay Compared With the Clinical Diagnosis of Vaginitis — uas qhia cov kev tshawb pom los ntawm BD soj ntsuam sim — peb ua rau vaginitis (kab mob vaginosis [BV], vulvovaginal candidiasis [VVC] los yog Trichomonas vaginalis [TV ]) tau kawm los sib piv cov kev ntsuam xyuas kws kho mob nrog cov txiaj ntsig los ntawm kev sim tshuaj molecular. Txoj kev tshawb nrhiav pom tias piv rau qhov kev sim tshuaj molecular, tus kws kho mob kuaj pom tsis tau 45.3 feem pua ​​​​ntawm cov neeg mob zoo (180 ntawm 397) thiab tsis raug txheeb xyuas 12.3 feem pua ​​​​ntawm cov neeg mob tsis zoo (123 ntawm 879).

Txoj kev tshawb no tseem raug xaiv los koom nrog hauv Obstetrics & Gynecology Journal Club, uas xaiv ob mus rau peb qhov kev tshawb fawb ib qhov teeb meem los muab cov tub ntxhais kawm kho mob saib xyuas cov ntaub ntawv pov thawj thiab pab lawv tsim lub hauv paus rau kev xyaum ua pov thawj.

Nyob nruab nrab ntawm 6 lab thiab 10 lab mus saib xyuas kev noj qab haus huv los ntawm cov poj niam hauv Teb Chaws Asmeskas muaj feem cuam tshuam rau cov tsos mob ntawm vaginitis.1,2 Txawm hais tias vaginitis yog ib qho mob tshwm sim, kev kuaj mob ntawm nws ib txwm ua rau 3,4 (BV, VVC, lossis TV) hauv cov poj niam ntawm kev xeeb tub. hnub nyoog tsis yog tus qauv.

"Kev kuaj mob tsis zoo txhais tau hais tias cov lus pom zoo kho tsis tsim nyog - txawm tias kev kho tsis zoo lossis kev kho mob ntau dhau," hais tias kev tshawb fawb tus kws sau ntawv Molly Broache, kws kho mob kev sib tham rau Kev Tshawb Fawb Kev Sib Koom ntawm BD. "Ib tug poj niam yuav raug hais kom rov mus ntsib kws kho mob uas tsis tsim nyog, lossis nws tuaj yeem txhim kho cov tshuaj tiv thaiv kab mob vim tias nws tau noj tshuaj tua kab mob uas nws tsis xav tau tiag tiag."

Txoj kev tshawb no piv cov kws kho mob kuaj mob ntawm vaginitis rau cov txiaj ntsig ntawm qhov chaw kuaj mob ntawm qhov chaw mos ua nyob rau ntawm BD MAX™ System, FDA-kev ua lag luam tso cai kuaj molecular uas siv nucleic acid amplification los xyuas cov microbial ua rau BV, VVC, thiab TV. Txoj kev tshawb no koom nrog 489 tus neeg koom nrog cov tsos mob. Cov neeg tuaj koom tau txais kev kuaj mob thiab tau txais ib qho tshuaj ntsuam xyuas qhov chaw mos thaum lawv mus ntsib. Swabs raug xa mus rau qhov chaw sim cais thiab tom qab ntawd piv rau cov kws kho mob kuaj mob.

"Peb yeej ua rau cov poj niam tsis muaj kev kho mob thaum peb tsis siv cov cuab yeej zoo tshaj plaws uas peb muaj los kuaj xyuas qhov ua rau lossis ua rau cov tsos mob uas ua rau lawv mus nrhiav kev kho mob," hais tias kev tshawb fawb co-sau Barbara Van Der Pol, Ph.D ., MPH thiab xibfwb ntawm Tshuaj thiab Kev Noj Qab Haus Huv. "Kev kis mob ntau dhau yog tshwm sim los ntawm ntau yam kab mob rau peb xav tias peb tuaj yeem txheeb xyuas lawv kom raug yam tsis muaj kev kuaj mob zoo. Cov ntaub ntawv hauv daim ntawv no lees paub tias peb tshuav cov poj niam txoj kev xaiv zoo tshaj plaws muaj thiab kev soj ntsuam kev soj ntsuam tsis txaus. "

BD MAX™ Vaginal Panel Assay tuaj yeem pab daws cov kev txwv ntawm kev kuaj mob thiab tuaj yeem pab txhim kho qhov tseeb ntawm kev kuaj mob. Qhov kev ntsuam xyuas tsis siv neeg no muaj lub sijhawm luv luv (kwv yees li peb teev los khiav ntawm ob thiab 24 cov qauv ib txhij), yog li cov txiaj ntsig tib hnub tuaj yeem ua tau yog tus kws kho mob muaj cov cuab yeej muaj nyob rau ntawm qhov chaw. Assay automation yog tsim los txo qhov sib txawv thiab cov ntsiab lus, yog li pab txhawm rau txhim kho qhov tseeb.

"Thaum tus poj niam raug kuaj pom tsis raug rau ib txoj kev - hais tias nws tsis muaj vaginitis tab sis ua tiag tiag lossis qhia tias nws muaj vaginitis tab sis tsis kis - nws tsim kev nyuaj thiab pheej hmoo," Broache hais. "Cov poj niam tsim nyog zoo dua."

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